Structural highlights
Function
HEPC_BACTN Specifically cleaves heparan sulfate-rich regions of acidic polysaccharides. Does not act on N,O-desulfated glucosamine or N-acetyl-O-sulfated glucosamine linkages. Functions in cleaving metazoan heparan sulfate and providing carbon, nitrogen and sulfate sources for microorganisms.[1]
References
- ↑ Dong W, Lu W, McKeehan WL, Luo Y, Ye S. Structural basis of heparan sulfate-specific degradation by heparinase III. Protein Cell. 2012 Jul 21. PMID:23011846 doi:http://dx.doi.org/10.1007/s13238-012-2056-z
