4lh3

Structural highlights

Function

AL4A1_MOUSE Irreversible conversion of delta-1-pyrroline-5-carboxylate (P5C), derived either from proline or ornithine, to glutamate. This is a necessary step in the pathway interconnecting the urea and tricarboxylic acid cycles. The preferred substrate is glutamic gamma-semialdehyde, other substrates include succinic, glutaric and adipic semialdehydes (By similarity).

See Also

• Aldehyde dehydrogenase 3D structures
• Pyrroline-5-carboxylate dehydrogenase