4rkm

Structural highlights

Function

MCCA_WOLSU Respiratory sulfite reductase that catalyzes the reduction of sulfite to sulfide in a single step, consuming six electrons in the process (PubMed:22040142, PubMed:25642962). Required for sulfite respiration under anaerobic growth conditions (PubMed:22040142). Has only marginal activity with nitrite.^{[1] [2]}

References

1. ↑ Kern M, Klotz MG, Simon J. The Wolinella succinogenes mcc gene cluster encodes an unconventional respiratory sulphite reduction system. Mol Microbiol. 2011 Dec;82(6):1515-30. PMID:22040142 doi:10.1111/j.1365-2958.2011.07906.x
2. ↑ Hermann B, Kern M, La Pietra L, Simon J, Einsle O. The octahaem MccA is a haem c-copper sulfite reductase. Nature. 2015 Feb 2. doi: 10.1038/nature14109. PMID:25642962 doi:http://dx.doi.org/10.1038/nature14109