4u6n

Structural highlights

Function

DIAA_ECOLI Required for the timely initiation of chromosomal replication via direct interactions with the DnaA initiator protein.^{[1] [2]}

References

1. ↑ Ishida T, Akimitsu N, Kashioka T, Hatano M, Kubota T, Ogata Y, Sekimizu K, Katayama T. DiaA, a novel DnaA-binding protein, ensures the timely initiation of Escherichia coli chromosome replication. J Biol Chem. 2004 Oct 29;279(44):45546-55. Epub 2004 Aug 23. PMID:15326179 doi:http://dx.doi.org/10.1074/jbc.M402762200
2. ↑ Keyamura K, Fujikawa N, Ishida T, Ozaki S, Su'etsugu M, Fujimitsu K, Kagawa W, Yokoyama S, Kurumizaka H, Katayama T. The interaction of DiaA and DnaA regulates the replication cycle in E. coli by directly promoting ATP DnaA-specific initiation complexes. Genes Dev. 2007 Aug 15;21(16):2083-99. PMID:17699754 doi:21/16/2083