Structural highlights
Function
MOSP_RUMA7 Catalyzes the phosphorolysis of beta-1,4-mannooligosaccharides to mannose 1-phosphate (Man1P) and shorter mannooligosaccharides. Can also catalyze the phosphorolysis of 4-O-beta-D-mannopyranosyl-D-glucopyranose (Man-Glc), but shows higher activity toward longer mannooligosaccharides. Involved in a mannan catabolic pathway which feeds into glycolysis.[1]
References
- ↑ Kawahara R, Saburi W, Odaka R, Taguchi H, Ito S, Mori H, Matsui H. Metabolic mechanism of mannan in a ruminal bacterium, Ruminococcus albus, involving two mannoside phosphorylases and cellobiose 2-epimerase: discovery of a new carbohydrate phosphorylase, beta-1,4-mannooligosaccharide phosphorylase. J Biol Chem. 2012 Dec 7;287(50):42389-99. doi: 10.1074/jbc.M112.390336. Epub 2012, Oct 23. PMID:23093406 doi:http://dx.doi.org/10.1074/jbc.M112.390336
