Structural highlights
Function
DIXC1_MOUSE Positive effector of the Wnt signaling pathway; activates WNT3A signaling via DVL2. Regulates JNK activation by AXIN1 and DVL2.[1] [2]
References
- ↑ Wong CK, Luo W, Deng Y, Zou H, Ye Z, Lin SC. The DIX domain protein coiled-coil-DIX1 inhibits c-Jun N-terminal kinase activation by Axin and dishevelled through distinct mechanisms. J Biol Chem. 2004 Sep 17;279(38):39366-73. Epub 2004 Jul 15. PMID:15262978 doi:http://dx.doi.org/10.1074/jbc.M404598200
- ↑ Shiomi K, Kanemoto M, Keino-Masu K, Yoshida S, Soma K, Masu M. Identification and differential expression of multiple isoforms of mouse Coiled-coil-DIX1 (Ccd1), a positive regulator of Wnt signaling. Brain Res Mol Brain Res. 2005 Apr 27;135(1-2):169-80. Epub 2005 Jan 27. PMID:15857680 doi:http://dx.doi.org/S0169-328X(04)00623-0
