Structural highlights
Function
CYPH1_SALMI Cytochrome P450 enzyme (CYP) which catalyzes a unique two-electron oxidation cascade on abieta-8,11,13-triene to produce ferruginol, an intermediate in tanshinone biosynthesis.[1]
References
- ↑ Guo J, Zhou YJ, Hillwig ML, Shen Y, Yang L, Wang Y, Zhang X, Liu W, Peters RJ, Chen X, Zhao ZK, Huang L. CYP76AH1 catalyzes turnover of miltiradiene in tanshinones biosynthesis and enables heterologous production of ferruginol in yeasts. Proc Natl Acad Sci U S A. 2013 Jul 16;110(29):12108-13. doi:, 10.1073/pnas.1218061110. Epub 2013 Jun 28. PMID:23812755 doi:http://dx.doi.org/10.1073/pnas.1218061110
