5ymr

Structural highlights

Function

ISLA_DESVH Involved in an anaerobic respiration pathway that converts the sulfonate isethionate (2-hydroxyethanesulfonate) to ammonia, acetate and sulfide. Catalyzes the radical-mediated C-S bond cleavage of isethionate (2-hydroxyethanesulfonate) to form sulfite and acetaldehyde. Shows no activity with taurine or ethanolamine as substrates.^[1]

References

1. ↑ Xing M, Wei Y, Zhou Y, Zhang J, Lin L, Hu Y, Hua G, N Nanjaraj Urs A, Liu D, Wang F, Guo C, Tong Y, Li M, Liu Y, Ang EL, Zhao H, Yuchi Z, Zhang Y. Radical-mediated C-S bond cleavage in C2 sulfonate degradation by anaerobic bacteria. Nat Commun. 2019 Apr 8;10(1):1609. doi: 10.1038/s41467-019-09618-8. PMID:30962433 doi:http://dx.doi.org/10.1038/s41467-019-09618-8