6bk2

Structural highlights

Function

UGT79_ORYSJ Involved in the detoxification of the Fusarium mycotoxin deoxynivalenol by the transfer of glucose from UDP-D-glucose to the hydroxyl group at C-3, forming deoxynivalenol-3-O-beta-D-glucoside.^{[1] [2]}

See Also

• Glycosyltransferase 3D structures

References

1. ↑ Michlmayr H, Malachova A, Varga E, Kleinova J, Lemmens M, Newmister S, Rayment I, Berthiller F, Adam G. Biochemical Characterization of a Recombinant UDP-glucosyltransferase from Rice and Enzymatic Production of Deoxynivalenol-3-O-beta-D-glucoside. Toxins (Basel). 2015 Jul 21;7(7):2685-700. doi: 10.3390/toxins7072685. PMID:26197338 doi:http://dx.doi.org/10.3390/toxins7072685
2. ↑ Wetterhorn KM, Newmister SA, Caniza RK, Busman M, McCormick SP, Berthiller F, Adam G, Rayment I. Crystal structure of Os79 (Os04g0206600) from Oryza sativa: A UDP-glucosyltransferase involved in the detoxification of deoxynivalenol. Biochemistry. 2016 Oct 7. PMID:27715009 doi:http://dx.doi.org/10.1021/acs.biochem.6b00709