Structural highlights
6gmc is a 1 chain structure with sequence from Human. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
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Ligands: | , , |
Related: | 2nzl, 6gmb |
Gene: | HAO1, GOX1, HAOX1 (HUMAN) |
Activity: | (S)-2-hydroxy-acid oxidase, with EC number 1.1.3.15 |
Resources: | FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT |
Function
[HAOX1_HUMAN] Has 2-hydroxyacid oxidase activity. Most active on the 2-carbon substrate glycolate, but is also active on 2-hydroxy fatty acids, with high activity towards 2-hydroxy palmitate and 2-hydroxy octanoate.