6hla

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wild-type NuoEF from Aquifex aeolicus - reduced form bound to NADH

Structural highlights

6hla is a 4 chain structure with sequence from Aquifex aeolicus VF5. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 1.9Å
Ligands:FES, FMN, MPO, NA, NAD, SF4
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

NUOE_AQUAE NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity).

See Also

Contents


PDB ID 6hla

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OCA

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