Structural highlights
Function
CHAC2_HUMAN Catalyzes the cleavage of glutathione into 5-oxo-L-proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides.[1]
References
- ↑ Kaur A, Gautam R, Srivastava R, Chandel A, Kumar A, Karthikeyan S, Bachhawat AK. ChaC2: An Enzyme for Slow Turnover of Cytosolic Glutathione. J Biol Chem. 2016 Dec 2. pii: jbc.M116.727479. PMID:27913623 doi:http://dx.doi.org/10.1074/jbc.M116.727479