6l8w

Structural highlights

Function

74AC1_SIRGR Catalyzes the transfer of a glucose moiety to the C-3 hydroxyl of mogrol to form mogroside IE (PubMed:25759326, Ref.3). Besides mogrol, UGT74AC1 also shows activity in vitro with quercetin and naringenin as substrate (PubMed:25759326).^{[1] [2]}

See Also

• Glycosyltransferase 3D structures

References

1. ↑ Dai L, Liu C, Zhu Y, Zhang J, Men Y, Zeng Y, Sun Y. Functional Characterization of Cucurbitadienol Synthase and Triterpene Glycosyltransferase Involved in Biosynthesis of Mogrosides from Siraitia grosvenorii. Plant Cell Physiol. 2015 Jun;56(6):1172-82. PMID:25759326 doi:10.1093/pcp/pcv043
2. ↑ Dai L, Liu C, Zhu Y, Zhang J, Men Y, Zeng Y, Sun Y. Functional Characterization of Cucurbitadienol Synthase and Triterpene Glycosyltransferase Involved in Biosynthesis of Mogrosides from Siraitia grosvenorii. Plant Cell Physiol. 2015 Jun;56(6):1172-82. PMID:25759326 doi:10.1093/pcp/pcv043