Structural highlights
Function
SAV_STRAV The biological function of streptavidin is not known. Forms a strong non-covalent specific complex with biotin (one molecule of biotin per subunit of streptavidin).
Publication Abstract from PubMed
We utilized electrostatic interaction to induce rapid crystallization of streptavidin. Simply mixing streptavidins possessing either a positively or negatively charged peptide at their C-terminus generated diffraction-quality crystals in a few hours. We modified the streptavidin crystals with fluorescent molecules using biotin, demonstrating the concept of protein crystals as functional biomaterials.
Genetically fused charged peptides induce rapid crystallization of proteins.,Minamihata K, Tsukamoto K, Adachi M, Shimizu R, Mishina M, Kuroki R, Nagamune T Chem Commun (Camb). 2020 Mar 5. doi: 10.1039/c9cc09529b. PMID:32134050[1]
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.
See Also
References
- ↑ Minamihata K, Tsukamoto K, Adachi M, Shimizu R, Mishina M, Kuroki R, Nagamune T. Genetically fused charged peptides induce rapid crystallization of proteins. Chem Commun (Camb). 2020 Mar 5. doi: 10.1039/c9cc09529b. PMID:32134050 doi:http://dx.doi.org/10.1039/c9cc09529b
