6v0m

Structural highlights

Function

M3K15_HUMAN May function in a signal transduction pathway that is activated by various cell stresses and leads to apoptosis.^[1]

See Also

• Mitogen-activated protein kinase kinase kinase

References

1. ↑ Kaji T, Yoshida S, Kawai K, Fuchigami Y, Watanabe W, Kubodera H, Kishimoto T. ASK3, a novel member of the apoptosis signal-regulating kinase family, is essential for stress-induced cell death in HeLa cells. Biochem Biophys Res Commun. 2010 Apr 30;395(2):213-8. doi:, 10.1016/j.bbrc.2010.03.164. Epub 2010 Apr 1. PMID:20362554 doi:http://dx.doi.org/10.1016/j.bbrc.2010.03.164