6xod

Structural highlights

Function

PEX4_ARATH Required for peroxisome biogenesis. Necessary for the developmental elimination of obsolete peroxisome matrix proteins. May be involved in the ubiquitination of PEX5, targeting it for recycling. Accepts the ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins.^{[1] [2]}

References

1. ↑ Nito K, Kamigaki A, Kondo M, Hayashi M, Nishimura M. Functional classification of Arabidopsis peroxisome biogenesis factors proposed from analyses of knockdown mutants. Plant Cell Physiol. 2007 Jun;48(6):763-74. PMID:17478547 doi:10.1093/pcp/pcm053
2. ↑ Lingard MJ, Monroe-Augustus M, Bartel B. Peroxisome-associated matrix protein degradation in Arabidopsis. Proc Natl Acad Sci U S A. 2009 Mar 17;106(11):4561-6. PMID:19246395 doi:10.1073/pnas.0811329106