Structural highlights
6zk8 is a 2 chain structure with sequence from Methanothermococcus thermolithotrophicus. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
|
| Method: | X-ray diffraction, Resolution 1.83Å |
| Ligands: | , , , , |
| Resources: | FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT |
Function
A0A452CSW8_METTL
Publication Abstract from PubMed
F420H2-oxidase (FprA) catalyses the four-electron reduction of O2 to 2H2O using the reduced form of F420 as electron donor. The hydrophobic O2-channel detected by Kr-derivatization and the concerted movement of a gating loop could contribute to prevent unwanted side-reaction between the catalytic intermediates and solvents, therefore preventing reactive oxygen species formation.
Krypton-derivatization highlights O2-channeling in a four-electron reducing oxidase.,Engilberge S, Wagner T, Carpentier P, Girard E, Shima S Chem Commun (Camb). 2020 Sep 17;56(74):10863-10866. doi: 10.1039/d0cc04557h. PMID:32940290[1]
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.
References
- ↑ Engilberge S, Wagner T, Carpentier P, Girard E, Shima S. Krypton-derivatization highlights O(2)-channeling in a four-electron reducing oxidase. Chem Commun (Camb). 2020 Sep 17;56(74):10863-10866. PMID:32940290 doi:10.1039/d0cc04557h
