Structural highlights
7a0c is a 2 chain structure with sequence from Escherichia coli K-12. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
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| Method: | X-ray diffraction, Resolution 1.9Å |
| Ligands: | , , , , , |
| Resources: | FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT |
Function
NIKA_ECOLI Involved in a nickel transport system, probably represents the nickel binder.
Publication Abstract from PubMed
Performing a heterogeneous catalysis with proteins is still a challenge. Here, we demonstrate the importance of cross-linked crystals for sulfoxide oxidation by an artificial enzyme. The biohybrid consists of the insertion of an iron complex into a NikA protein crystal. The heterogeneous catalysts displays a better efficiency-with higher reaction kinetics, a better stability and expand the substrate scope compared to its solution counterpart. Designing crystalline artificial enzymes represents a good alternative to soluble or supported enzymes for the future of synthetic biology.
A Selective Sulfide Oxidation catalyzed by Heterogeneous Artificial Enzymes Iron@NikA.,Menage S, Lopez S, Marchi-Delapierre C, Cavazza C Chemistry. 2020 Oct 20. doi: 10.1002/chem.202003746. PMID:33079395[1]
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.
See Also
References
- ↑ Menage S, Lopez S, Marchi-Delapierre C, Cavazza C. A Selective Sulfide Oxidation catalyzed by Heterogeneous Artificial Enzymes Iron@NikA. Chemistry. 2020 Oct 20. doi: 10.1002/chem.202003746. PMID:33079395 doi:http://dx.doi.org/10.1002/chem.202003746
