Structural highlights
7cn3 is a 6 chain structure with sequence from Pseudomonas putida KT2440. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
|
Method: | X-ray diffraction, Resolution 2.2Å |
Ligands: | , , , , |
Resources: | FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT |
Function
NICX_PSEPK Catalyzes the dioxygenolytic ring cleavage of 2,5-dihydroxypyridine between carbons 5 and 6 generating N-formylmaleamate in the aerobic nicotinate degradation pathway.[1]
References
- ↑ Jimenez JI, Canales A, Jimenez-Barbero J, Ginalski K, Rychlewski L, Garcia JL, Diaz E. Deciphering the genetic determinants for aerobic nicotinic acid degradation: the nic cluster from Pseudomonas putida KT2440. Proc Natl Acad Sci U S A. 2008 Aug 12;105(32):11329-34. doi:, 10.1073/pnas.0802273105. Epub 2008 Aug 4. PMID:18678916 doi:http://dx.doi.org/10.1073/pnas.0802273105