Crystal Structure of rat Autotaxin in complex with 6-chloro-3-[5-cyclopropyl-6-(oxan-4-yloxy)pyridin-3-yl]-1H-pyrazolo[3,4-b]pyridine, i.e. SMILES N1=C(c2c(N1)nc(cc2)Cl)c1cc(c(nc1)OC1CCOCC1)C1CC1 with IC50=1.82666 microM
7g6s is a 1 chain structure with sequence from Rattus norvegicus. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
