7hr8

Structural highlights

Function

FATA1_ARATH Plays an essential role in chain termination during de novo fatty acid synthesis. Possesses high thioesterase activity for oleoyl-ACP versus other acyl-ACPs. Substrate preference is 18:1 > 18:0 > 16:1.^{[1] [2]}

References

1. ↑ Salas JJ, Ohlrogge JB. Characterization of substrate specificity of plant FatA and FatB acyl-ACP thioesterases. Arch Biochem Biophys. 2002 Jul 1;403(1):25-34. PMID:12061798 doi:10.1016/S0003-9861(02)00017-6
2. ↑ Moreno-Pérez AJ, Venegas-Calerón M, Vaistij FE, Salas JJ, Larson TR, Garcés R, Graham IA, Martínez-Force E. Reduced expression of FatA thioesterases in Arabidopsis affects the oil content and fatty acid composition of the seeds. Planta. 2012 Mar;235(3):629-39. PMID:22002626 doi:10.1007/s00425-011-1534-5