7mpy

Structural highlights

Function

FOLC_ARATH Catalyzes the first two consecutive steps of tetrahydrofolate biosynthesis (PubMed:17289662). Plays a role in seed stress response and survival (PubMed:17289662, PubMed:21996493).^{[1] [2]}

See Also

• HPPK 3D structures

References

1. ↑ Storozhenko S, Navarrete O, Ravanel S, De Brouwer V, Chaerle P, Zhang GF, Bastien O, Lambert W, Rebeille F, Van Der Straeten D. Cytosolic hydroxymethyldihydropterin pyrophosphokinase/dihydropteroate synthase from Arabidopsis thaliana: a specific role in early development and stress response. J Biol Chem. 2007 Apr 6;282(14):10749-61. doi: 10.1074/jbc.M701158200. Epub 2007 , Feb 8. PMID:17289662 doi:http://dx.doi.org/10.1074/jbc.M701158200
2. ↑ Navarrete O, Van Daele J, Stove C, Lambert W, Van Der Straeten D, Storozhenko S. A folate independent role for cytosolic HPPK/DHPS upon stress in Arabidopsis thaliana. Phytochemistry. 2012 Jan;73(1):23-33. doi: 10.1016/j.phytochem.2011.09.008. Epub , 2011 Oct 11. PMID:21996493 doi:http://dx.doi.org/10.1016/j.phytochem.2011.09.008