7n2t

Structural highlights

Function

CYSK_CITLA Produces L-cysteine from O-acetyl-L-serine and hydrogen sulfide. Can also use pyrazole and 3,4-dihydroxypyridine instead of the hydrogen sulfide to produce two plant specific non-protein amino acids beta-pyrazolylalanine and L-mimosine.^{[1] [2]}

References

1. ↑ Noji M, Murakoshi I, Saito K. Evidence for identity of beta-pyrazolealanine synthase with cysteine synthase in watermelon: formation of beta-pyrazole-alanine by cloned cysteine synthase in vitro and in vivo. Biochem Biophys Res Commun. 1993 Dec 30;197(3):1111-7. PMID:8280125 doi:http://dx.doi.org/S0006-291X(83)72592-1
2. ↑ Saito K, Kimura N, Ikegami F, Noji M. Production of plant non-protein amino acids by recombinant enzymes of sequential biosynthetic reactions in bacteria. Biol Pharm Bull. 1997 Jan;20(1):47-53. PMID:9013806