7rsf

Structural highlights

Function

ARGE_ECOLI Catalyzes the hydrolysis of the amide bond of N(2)-acetylated L-amino acids. Cleaves the acetyl group from N-acetyl-L-ornithine to form L-ornithine, an intermediate in L-arginine biosynthesis pathway, and a branchpoint in the synthesis of polyamines.[HAMAP-Rule:MF_01108]^{[1] [2]}

References

1. ↑ Javid-Majd F, Blanchard JS. Mechanistic analysis of the argE-encoded N-acetylornithine deacetylase. Biochemistry. 2000 Feb 15;39(6):1285-93. PMID:10684608 doi:10.1021/bi992177f
2. ↑ Meinnel T, Schmitt E, Mechulam Y, Blanquet S. Structural and biochemical characterization of the Escherichia coli argE gene product. J Bacteriol. 1992 Apr;174(7):2323-31. PMID:1551850 doi:10.1128/jb.174.7.2323-2331.1992