We apologize for Proteopedia being slow to respond. For the past two years, a new implementation of Proteopedia has been being built. Soon, it will replace this 18-year old system. All existing content will be moved to the new system at a date that will be announced here.
7sfz is a 8 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
MS18A_HUMAN Required for recruitment of CENPA to centromeres and normal chromosome segregation during mitosis.[1]
References
↑ Fujita Y, Hayashi T, Kiyomitsu T, Toyoda Y, Kokubu A, Obuse C, Yanagida M. Priming of centromere for CENP-A recruitment by human hMis18alpha, hMis18beta, and M18BP1. Dev Cell. 2007 Jan;12(1):17-30. doi: 10.1016/j.devcel.2006.11.002. PMID:17199038 doi:http://dx.doi.org/10.1016/j.devcel.2006.11.002