Structural highlights
Function
NSE1_YEAST Acts in a DNA repair pathway for removal of UV-induced DNA damage that is distinct from classical nucleotide excision repair and in repair of ionizing radiation damage. Functions in homologous recombination repair of DNA double strand breaks and in recovery of stalled replication forks.[1]
References
- ↑ Fujioka Y, Kimata Y, Nomaguchi K, Watanabe K, Kohno K. Identification of a novel non-structural maintenance of chromosomes (SMC) component of the SMC5-SMC6 complex involved in DNA repair. J Biol Chem. 2002 Jun 14;277(24):21585-91. PMID:11927594 doi:10.1074/jbc.M201523200