7vp3

Structural highlights

Function

TCP15_ARATH Transcription factor involved the regulation of plant development. Together with TCP14, modulates plant stature by promoting cell division in young internodes. Represses cell proliferation in developing leaf blade and specific floral tissues (PubMed:21668538). Together with TCP15, acts downstream of gibberellin (GA), and the stratification pathways that promote seed germination. Involved in the control of cell proliferation at the root apical meristem (RAM) by regulating the activity of CYCB1-1 (PubMed:25655823). Acts together with SPY to promote cytokinin responses that affect leaf shape and trichome development in flowers (PubMed:22267487). Involved in gynoecium and silique development. Modulates the development of the different tissues of the gynoecium through its participation in auxin and cytokinin responses. Modulates the expression of the cytokinin-responsive genes ARR7 and ARR15. May repress the expression of the auxin biosynthetic genes YUC1 and YUC4 (PubMed:26303297). Acts as negative regulator of anthocyanin accumulation under high light conditions. Modulates the expression of transcription factors involved in the induction of anthocyanin biosynthesis genes (PubMed:26574599). Transcription factor involved in the regulation of endoreduplication. Represses endoreduplication by activating the gene expression of the key cell-cycle regulators RBR1 and CYCA2-3 (PubMed:25757472). Regulates the expression of the defense gene pathogenesis-related protein 2 (PR2) in antagonism to SRFR1, a negative regulator of effector-triggered immunity (PubMed:24689742).^{[1] [2] [3] [4] [5] [6] [7]}

References

1. ↑ Kieffer M, Master V, Waites R, Davies B. TCP14 and TCP15 affect internode length and leaf shape in Arabidopsis. Plant J. 2011 Oct;68(1):147-58. doi: 10.1111/j.1365-313X.2011.04674.x. Epub 2011 , Jul 21. PMID:21668538 doi:http://dx.doi.org/10.1111/j.1365-313X.2011.04674.x
2. ↑ Steiner E, Efroni I, Gopalraj M, Saathoff K, Tseng TS, Kieffer M, Eshed Y, Olszewski N, Weiss D. The Arabidopsis O-linked N-acetylglucosamine transferase SPINDLY interacts with class I TCPs to facilitate cytokinin responses in leaves and flowers. Plant Cell. 2012 Jan;24(1):96-108. doi: 10.1105/tpc.111.093518. Epub 2012 Jan 20. PMID:22267487 doi:http://dx.doi.org/10.1105/tpc.111.093518
3. ↑ Kim SH, Son GH, Bhattacharjee S, Kim HJ, Nam JC, Nguyen PD, Hong JC, Gassmann W. The Arabidopsis immune adaptor SRFR1 interacts with TCP transcription factors that redundantly contribute to effector-triggered immunity. Plant J. 2014 Jun;78(6):978-89. doi: 10.1111/tpj.12527. Epub 2014 May 23. PMID:24689742 doi:http://dx.doi.org/10.1111/tpj.12527
4. ↑ Resentini F, Felipo-Benavent A, Colombo L, Blazquez MA, Alabadi D, Masiero S. TCP14 and TCP15 mediate the promotion of seed germination by gibberellins in Arabidopsis thaliana. Mol Plant. 2015 Mar;8(3):482-5. doi: 10.1016/j.molp.2014.11.018. Epub 2014 Dec, 17. PMID:25655823 doi:http://dx.doi.org/10.1016/j.molp.2014.11.018
5. ↑ Peng Y, Chen L, Lu Y, Wu Y, Dumenil J, Zhu Z, Bevan MW, Li Y. The ubiquitin receptors DA1, DAR1, and DAR2 redundantly regulate endoreduplication by modulating the stability of TCP14/15 in Arabidopsis. Plant Cell. 2015 Mar;27(3):649-62. doi: 10.1105/tpc.114.132274. Epub 2015 Mar 10. PMID:25757472 doi:http://dx.doi.org/10.1105/tpc.114.132274
6. ↑ Lucero LE, Uberti-Manassero NG, Arce AL, Colombatti F, Alemano SG, Gonzalez DH. TCP15 modulates cytokinin and auxin responses during gynoecium development in Arabidopsis. Plant J. 2015 Oct;84(2):267-82. doi: 10.1111/tpj.12992. PMID:26303297 doi:http://dx.doi.org/10.1111/tpj.12992
7. ↑ Viola IL, Camoirano A, Gonzalez DH. Redox-Dependent Modulation of Anthocyanin Biosynthesis by the TCP Transcription Factor TCP15 during Exposure to High Light Intensity Conditions in Arabidopsis. Plant Physiol. 2016 Jan;170(1):74-85. doi: 10.1104/pp.15.01016. Epub 2015 Nov 16. PMID:26574599 doi:http://dx.doi.org/10.1104/pp.15.01016