Structural highlights
Function
UBP54_HUMAN Deubiquitinating enzyme which mediates deubiquitination of PLK4, maintaining PLK4 stability by reducing its ubiquitination-mediated degradation.[1]
References
- ↑ Zhang C, Ma X, Wei G, Zhu X, Hu P, Chen X, Wang D, Li Y, Ruan T, Zhang W, Tao K, Wu C. Centrosomal protein 120 promotes centrosome amplification and gastric cancer progression via USP54-mediated deubiquitination of PLK4. iScience. 2022 Dec 7;26(1):105745. PMID:36590171 doi:10.1016/j.isci.2022.105745
