8db0

Structural highlights

Function

DMAT1_GIBF5 Dimethylallyltryptophan synthase; part of the DMATS1 gene cluster that mediates the biosynthesis of a reversely N-prenylated monomeric L-tryptophan (r-N-DMAT) (PubMed:28295904). The main product of the cluster is the r-N-DMAT produced by the dimethylallyltryptophan synthase DMATS1 and it remains unclear whether this metabolite undergoes further modifications when silent gene clusters are activated (PubMed:28295904). The acetylated form of r-N-DMAT, ac-r-N-DMAT, is also produced (PubMed:28295904). The roles of the cytochrome P450 monooxygenase FFUJ_09176 and the methyltransferase FFUJ_09178 have still to be elucidated (Probable).^{[1] [2]}

References

1. ↑ Arndt B, Janevska S, Schmid R, Hubner F, Tudzynski B, Humpf HU. A Fungal N-Dimethylallyltryptophan Metabolite from Fusarium fujikuroi. Chembiochem. 2017 May 18;18(10):899-904. doi: 10.1002/cbic.201600691. Epub 2017, Apr 13. PMID:28295904 doi:http://dx.doi.org/10.1002/cbic.201600691
2. ↑ Arndt B, Janevska S, Schmid R, Hubner F, Tudzynski B, Humpf HU. A Fungal N-Dimethylallyltryptophan Metabolite from Fusarium fujikuroi. Chembiochem. 2017 May 18;18(10):899-904. doi: 10.1002/cbic.201600691. Epub 2017, Apr 13. PMID:28295904 doi:http://dx.doi.org/10.1002/cbic.201600691