8gbs

Structural highlights

Function

GVPA_DOLFA Gas vesicles (GV) are hollow, gas filled proteinaceous nanostructures found in some microorganisms. During planktonic growth they allow positioning of the organism at a favorable depth for light or nutrient acquisition. GVs are highly permeable to gas (Ref.7). GvpA forms the protein shell (PubMed:14695294, PubMed:1527496, PubMed:20858439, PubMed:22147705, PubMed:3098234, PubMed:3141741, PubMed:6409075, Ref.5). The ratio of GvpA:GvpC is estimated to be 33:1 and more recently 25:1 (PubMed:3141741, PubMed:8254305).^{[1] [2] [3] [4] [5] [6] [7] [8] [9] [10] [11]}

References

1. ↑ Belenky M, Meyers R, Herzfeld J. Subunit structure of gas vesicles: a MALDI-TOF mass spectrometry study. Biophys J. 2004 Jan;86(1 Pt 1):499-505. PMID:14695294 doi:10.1016/S0006-3495(04)74128-4
2. ↑ Griffiths AE, Walsby AE, Hayes PK. The homologies of gas vesicle proteins. J Gen Microbiol. 1992 Jun;138(6):1243-50. PMID:1527496 doi:10.1099/00221287-138-6-1243
3. ↑ Sivertsen AC, Bayro MJ, Belenky M, Griffin RG, Herzfeld J. Solid-state NMR characterization of gas vesicle structure. Biophys J. 2010 Sep 22;99(6):1932-9. PMID:20858439 doi:10.1016/j.bpj.2010.06.041
4. ↑ Bayro MJ, Daviso E, Belenky M, Griffin RG, Herzfeld J. An amyloid organelle, solid-state NMR evidence for cross-β assembly of gas vesicles. J Biol Chem. 2012 Jan 27;287(5):3479-84. PMID:22147705 doi:10.1074/jbc.M111.313049
5. ↑ Hayes PK, Walsby AE, Walker JE. Complete amino acid sequence of cyanobacterial gas-vesicle protein indicates a 70-residue molecule that corresponds in size to the crystallographic unit cell. Biochem J. 1986 May 15;236(1):31-6. PMID:3098234 doi:10.1042/bj2360031
6. ↑ Hayes PK, Lazarus CM, Bees A, Walker JE, Walsby AE. The protein encoded by gvpC is a minor component of gas vesicles isolated from the cyanobacteria Anabaena flos-aquae and Microcystis sp. Mol Microbiol. 1988 Sep;2(5):545-52. PMID:3141741 doi:10.1111/j.1365-2958.1988.tb00062.x
7. ↑ Walker JE, Walsby AE. Molecular weight of gas-vesicle protein from the planktonic cyanobacterium Anabaena flos-aquae and implications for structure of the vesicle. Biochem J. 1983 Mar 1;209(3):809-15. PMID:6409075 doi:10.1042/bj2090809
8. ↑ Buchholz BE, Hayes PK, Walsby AE. The distribution of the outer gas vesicle protein, GvpC, on the Anabaena gas vesicle, and its ratio to GvpA. J Gen Microbiol. 1993 Oct;139(10):2353-63. PMID:8254305 doi:10.1099/00221287-139-10-2353
9. ↑ Blaurock AE, Walsby AE. Crystalline structure of the gas vesicle wall from Anabaena flos-aquae. J Mol Biol. 1976 Aug 5;105(2):183-99. PMID:184286 doi:10.1016/0022-2836(76)90106-6
10. ↑ Sivertsen AC, Bayro MJ, Belenky M, Griffin RG, Herzfeld J. Solid-state NMR characterization of gas vesicle structure. Biophys J. 2010 Sep 22;99(6):1932-9. PMID:20858439 doi:10.1016/j.bpj.2010.06.041
11. ↑ Hayes PK, Lazarus CM, Bees A, Walker JE, Walsby AE. The protein encoded by gvpC is a minor component of gas vesicles isolated from the cyanobacteria Anabaena flos-aquae and Microcystis sp. Mol Microbiol. 1988 Sep;2(5):545-52. PMID:3141741 doi:10.1111/j.1365-2958.1988.tb00062.x