Structural highlights
Function
HBCAL_NITMS Involved in thaumarchaeal hydroxypropionate/hydroxybutyrate (HP/HB) cycle, a modified version of the autotrophic HP/HB cycle of Crenarchaeota. Catalyzes the formation of 4-hydroxybutyryl-CoA, ADP and phosphate from 4-hydroxybutyrate, coenzyme A (CoA) and ATP. Can also use acetate, propionate and butyrate, with poor catalytic efficiency.[1]
References
- ↑ Könneke M, Schubert DM, Brown PC, Hügler M, Standfest S, Schwander T, Schada von Borzyskowski L, Erb TJ, Stahl DA, Berg IA. Ammonia-oxidizing archaea use the most energy-efficient aerobic pathway for CO2 fixation. Proc Natl Acad Sci U S A. 2014 Jun 3;111(22):8239-44. PMID:24843170 doi:10.1073/pnas.1402028111