8j48

Structural highlights

Function

GAT18_ARATH Transcriptional factor that specifically binds 5'-GATA-3' or 5'-GAT-3' motifs within gene promoters (including its own promoter and GATA21 promoter), thus regulating the expression of genes mostly involved in hormone responses and floral organ specification (including genes regulating hormones responses) (PubMed:23335616, PubMed:26390296). Regulates both flower and shoot apical meristem (SAM) development, especially for establishing organ boundaries in shoots and flowers, probably by controlling the number and position of WUS-expressing cells (PubMed:15367721, PubMed:23335616). Coregulates, with AGO10/PNH, the shoot apical meristem (SAM) organization. Regulates floral organ development via the promotion of JAG and NPR5/BOP2 expression. Modulates cytokinin homeostasis in organ boundaries by regulating CKX3 expression (PubMed:26390296). Involved in cell proliferation and differentiation (PubMed:15367721). Required to position the inductive proembryo boundary via the regulation of gene expression and for early embryonic development (PubMed:20643354). Together with GIF1/AN3, mediates cotyledon identity by preventing ectopic root formation through the repression of PLT1 expression (PubMed:22669825).^{[1] [2] [3] [4] [5]}

References

1. ↑ Zhao Y, Medrano L, Ohashi K, Fletcher JC, Yu H, Sakai H, Meyerowitz EM. HANABA TARANU is a GATA transcription factor that regulates shoot apical meristem and flower development in Arabidopsis. Plant Cell. 2004 Oct;16(10):2586-600. PMID:15367721 doi:10.1105/tpc.104.024869
2. ↑ Nawy T, Bayer M, Mravec J, Friml J, Birnbaum KD, Lukowitz W. The GATA factor HANABA TARANU is required to position the proembryo boundary in the early Arabidopsis embryo. Dev Cell. 2010 Jul 20;19(1):103-13. PMID:20643354 doi:10.1016/j.devcel.2010.06.004
3. ↑ Kanei M, Horiguchi G, Tsukaya H. Stable establishment of cotyledon identity during embryogenesis in Arabidopsis by ANGUSTIFOLIA3 and HANABA TARANU. Development. 2012 Jul;139(13):2436-46. PMID:22669825 doi:10.1242/dev.081547
4. ↑ Zhang X, Zhou Y, Ding L, Wu Z, Liu R, Meyerowitz EM. Transcription repressor HANABA TARANU controls flower development by integrating the actions of multiple hormones, floral organ specification genes, and GATA3 family genes in Arabidopsis. Plant Cell. 2013 Jan;25(1):83-101. PMID:23335616 doi:10.1105/tpc.112.107854
5. ↑ Ding L, Yan S, Jiang L, Zhao W, Ning K, Zhao J, Liu X, Zhang J, Wang Q, Zhang X. HANABA TARANU (HAN) Bridges Meristem and Organ Primordia Boundaries through PINHEAD, JAGGED, BLADE-ON-PETIOLE2 and CYTOKININ OXIDASE 3 during Flower Development in Arabidopsis. PLoS Genet. 2015 Sep 21;11(9):e1005479. doi: 10.1371/journal.pgen.1005479., eCollection 2015 Sep. PMID:26390296 doi:http://dx.doi.org/10.1371/journal.pgen.1005479