8juk

Structural highlights

Function

V5VGC6_ACIBA Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.[ARBA:ARBA00024861][HAMAP-Rule:MF_01018]