8osq

Structural highlights

Function

GN_HHV11 Envelope glycoprotein necessary for proper maturation of gM and modulation of its membrane fusion activity. Also plays a critical role in virion morphogenesis.[HAMAP-Rule:MF_04037]^{[1] [2] [3]}

References

1. ↑ Mach M, Osinski K, Kropff B, Schloetzer-Schrehardt U, Krzyzaniak M, Britt W. The carboxy-terminal domain of glycoprotein N of human cytomegalovirus is required for virion morphogenesis. J Virol. 2007 May;81(10):5212-24. PMID:17229708 doi:10.1128/JVI.01463-06
2. ↑ El Kasmi I, Lippé R. Herpes simplex virus 1 gN partners with gM to modulate the viral fusion machinery. J Virol. 2015 Feb;89(4):2313-23. PMID:25505065 doi:10.1128/JVI.03041-14
3. ↑ Striebinger H, Funk C, Raschbichler V, Bailer SM. Subcellular Trafficking and Functional Relationship of the HSV-1 Glycoproteins N and M. Viruses. 2016 Mar 17;8(3):83. PMID:26999189 doi:10.3390/v8030083