8ox2

Structural highlights

Disease

PSPC_HUMAN Infant acute respiratory distress syndrome;Interstitial lung disease due to SP-C deficiency;Chronic respiratory distress with surfactant metabolism deficiency;Idiopathic pulmonary fibrosis. The disease is caused by variants affecting the gene represented in this entry.

Function

PSPC_HUMAN Pulmonary surfactant associated proteins promote alveolar stability by lowering the surface tension at the air-liquid interface in the peripheral air spaces.