Structural highlights
Function
NUOK_PARDP NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.[1]
References
- ↑ Stroh A, Anderka O, Pfeiffer K, Yagi T, Finel M, Ludwig B, Schägger H. Assembly of respiratory complexes I, III, and IV into NADH oxidase supercomplex stabilizes complex I in Paracoccus denitrificans. J Biol Chem. 2004 Feb 6;279(6):5000-7. PMID:14610094 doi:10.1074/jbc.M309505200
