Structural highlights
Function
PARA_MYXXD An essential component of the chromosome segregation machinery (PubMed:24466283). The ParABS system segregates newly replicated chromosomes during bacterial cell division. After DNA replication the ParB-parS partition complexes interact with ParA ATPase, promoting the movement of the origin region towards opposite cell poles. Segregation may be driven by rachet-like mechanism where ParB follows a retracting polar gradient of nucleoid-associated ParA (Probable) (PubMed:29180656).[1] [2]
References
- ↑ Iniesta AA. ParABS system in chromosome partitioning in the bacterium Myxococcus xanthus. PLoS One. 2014 Jan 22;9(1):e86897. PMID:24466283 doi:10.1371/journal.pone.0086897
- ↑ Lin L, Osorio Valeriano M, Harms A, Søgaard-Andersen L, Thanbichler M. Bactofilin-mediated organization of the ParABS chromosome segregation system in Myxococcus xanthus. Nat Commun. 2017 Nov 28;8(1):1817. PMID:29180656 doi:10.1038/s41467-017-02015-z
