8rvv

Structural highlights

Function

HDRA_METTM Part of a complex that catalyzes the reversible reduction of CoM-S-S-CoB to the thiol-coenzymes H-S-CoM (coenzyme M) and H-S-CoB (coenzyme B).^{[1] [2] [3]}

References

1. ↑ Hedderich R, Berkessel A, Thauer RK. Purification and properties of heterodisulfide reductase from Methanobacterium thermoautotrophicum (strain Marburg). Eur J Biochem. 1990 Oct 5;193(1):255-61. PMID:2121478 doi:10.1111/j.1432-1033.1990.tb19331.x
2. ↑ Kaster AK, Moll J, Parey K, Thauer RK. Coupling of ferredoxin and heterodisulfide reduction via electron bifurcation in hydrogenotrophic methanogenic archaea. Proc Natl Acad Sci U S A. 2011 Feb 15;108(7):2981-6. PMID:21262829 doi:10.1073/pnas.1016761108
3. ↑ Setzke E, Hedderich R, Heiden S, Thauer RK. H2: heterodisulfide oxidoreductase complex from Methanobacterium thermoautotrophicum. Composition and properties. Eur J Biochem. 1994 Feb 15;220(1):139-48. PMID:8119281 doi:10.1111/j.1432-1033.1994.tb18608.x