Structural highlights
Function
ZACN_HUMAN Ligand-gated cation channel that allows the movement of sodium and potassium monoatomic cations across cell membranes when activated by zinc (Zn2+), copper (Cu2+), and changes in pH (PubMed:26872532). Could also transport cesium (PubMed:26872532).[1]
References
- ↑ Trattnig SM, Gasiorek A, Deeb TZ, Ortiz EJ, Moss SJ, Jensen AA, Davies PA. Copper and protons directly activate the zinc-activated channel. Biochem Pharmacol. 2016 Mar 1;103:109-17. PMID:26872532 doi:10.1016/j.bcp.2016.02.004
