9bhx

Structural highlights

Function

7LESS_DROME Receptor for an extracellular signal required to instruct a cell to differentiate into an R7 photoreceptor. The ligand for sev is the boss (bride of sevenless) protein on the surface of the neighboring R8 cell.^[1]

References

1. ↑ Basler K, Hafen E. Control of photoreceptor cell fate by the sevenless protein requires a functional tyrosine kinase domain. Cell. 1988 Jul 29;54(3):299-311. PMID:2840202 doi:10.1016/0092-8674(88)90193-6