Structural highlights
Disease
PDYN_HUMAN Spinocerebellar ataxia type 23. The disease is caused by mutations affecting the gene represented in this entry.
Function
PDYN_HUMAN Leu-enkephalins compete with and mimic the effects of opiate drugs. They play a role in a number of physiologic functions, including pain perception and responses to stress (By similarity). Dynorphin peptides differentially regulate the kappa opioid receptor. Dynorphin A(1-13) has a typical opiod activity, it is 700 times more potent than Leu-enkephalin (By similarity). Leumorphin has a typical opiod activity and may have anti-apoptotic effect.
