Structural highlights
Function
GROA_MOUSE Has chemotactic activity for neutrophils. Contributes to neutrophil activation during inflammation (By similarity). Hematoregulatory chemokine, which, in vitro, suppresses hematopoietic progenitor cell proliferation. KC(5-72) shows a highly enhanced hematopoietic activity.[1]
References
- ↑ King AG, Johanson K, Frey CL, DeMarsh PL, White JR, McDevitt P, McNulty D, Balcarek J, Jonak ZL, Bhatnagar PK, Pelus LM. Identification of unique truncated KC/GRO beta chemokines with potent hematopoietic and anti-infective activities. J Immunol. 2000 Apr 1;164(7):3774-82. PMID:10725737