Structural highlights
Function
A0AA49QBA5_ASPNG Hydrolyzes malto-oligosaccharides, but has a low activity toward soluble starch.[ARBA:ARBA00056204]CPAO_ASPOR Beta-cyclopiazonate dehydrogenase involved in the synthesis of the fungal neurotoxin alpha-cyclopiazonic acid (CPA). CpaO carries out the dehydrogenation of beta-CPA to yield an unstable enimine product, which is captured by intramolecular cyclization to create the pentacyclic fused scaffold of alpha-cyclopiazonate.[1]
References
- ↑ Kato N, Tokuoka M, Shinohara Y, Kawatani M, Uramoto M, Seshime Y, Fujii I, Kitamoto K, Takahashi T, Takahashi S, Koyama Y, Osada H. Genetic safeguard against mycotoxin cyclopiazonic acid production in Aspergillus oryzae. Chembiochem. 2011 Jun 14;12(9):1376-82. PMID:21608094 doi:10.1002/cbic.201000672
