Structural highlights
Function
RES_PSEPK Toxic component of a type II toxin-antitoxin (TA) system. Expression in E.coli inhibits cell growth. In vivo it is probably neutralized by cognate antitoxin Xre; this has not been shown upon expression in E.coli (PubMed:30315706). Probably depletes intracellular NAD(+) (By similarity).[UniProtKB:Q7N4H9][1]
References
- ↑ Skjerning RB, Senissar M, Winther K, Gerdes K, Brodersen DE. The RES domain toxins of RES-Xre toxin-antitoxin modules induce cell stasis by degrading NAD(). Mol Microbiol. 2018 Oct 13. doi: 10.1111/mmi.14150. PMID:30315706 doi:http://dx.doi.org/10.1111/mmi.14150
