9sob

Structural highlights

Function

NU160_ARATH Contributes to the transfer of mature mRNA from the nucleus to the cytosol. Required for both R gene-mediated and basal disease resistance. RNA export seems to play a critical role in stress responses and regulation of plant growth and development. Required for proper expression of factors associated with auxin signaling.^{[1] [2] [3] [4] [5] [6]}

References

1. ↑ Parry G, Ward S, Cernac A, Dharmasiri S, Estelle M. The Arabidopsis SUPPRESSOR OF AUXIN RESISTANCE proteins are nucleoporins with an important role in hormone signaling and development. Plant Cell. 2006 Jul;18(7):1590-603. PMID:16751346 doi:10.1105/tpc.106.041566
2. ↑ Dong CH, Hu X, Tang W, Zheng X, Kim YS, Lee BH, Zhu JK. A putative Arabidopsis nucleoporin, AtNUP160, is critical for RNA export and required for plant tolerance to cold stress. Mol Cell Biol. 2006 Dec;26(24):9533-43. PMID:17030626 doi:10.1128/MCB.01063-06
3. ↑ Muthuswamy S, Meier I. Genetic and environmental changes in SUMO homeostasis lead to nuclear mRNA retention in plants. Planta. 2011 Jan;233(1):201-8. PMID:20872268 doi:10.1007/s00425-010-1278-7
4. ↑ Robles LM, Deslauriers SD, Alvarez AA, Larsen PB. A loss-of-function mutation in the nucleoporin AtNUP160 indicates that normal auxin signalling is required for a proper ethylene response in Arabidopsis. J Exp Bot. 2012 Mar;63(5):2231-41. PMID:22238449 doi:10.1093/jxb/err424
5. ↑ Wiermer M, Cheng YT, Imkampe J, Li M, Wang D, Lipka V, Li X. Putative members of the Arabidopsis Nup107-160 nuclear pore sub-complex contribute to pathogen defense. Plant J. 2012 Jun;70(5):796-808. PMID:22288649 doi:10.1111/j.1365-313X.2012.04928.x
6. ↑ Roth C, Wiermer M. Nucleoporins Nup160 and Seh1 are required for disease resistance in Arabidopsis. Plant Signal Behav. 2012 Oct 1;7(10):1212-4. PMID:22902705 doi:10.4161/psb.21426