9xvq

Structural highlights

Disease

NFIA_HUMAN 1p31p32 microdeletion syndrome. The disease is caused by variants affecting the gene represented in this entry.

Function

NFIA_HUMAN Recognizes and binds the palindromic sequence 5'-TTGGCNNNNNGCCAA-3' present in viral and cellular promoters and in the origin of replication of adenovirus type 2. These proteins are individually capable of activating transcription and replication.