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B-RAF with PLX4032

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B-RAF with PLX4032

PLX4032 is a newly synthesized drug that is being used to treat malignant melanoma with a specific mutation. The mutation is B-RAF^(V600E). This drug is highly selective for this mutation and will not bind to wild type B-RAF.


BRAF kinase domain complex with PLX4032 (PDB code 3og7)

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Proteopedia Page Contributors and Editors (what is this?)

J.D. Woodruff, Jens Hemmingsen, Michal Harel

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