Cardiotoxin
From Proteopedia
FunctionCardiotoxin or cytotoxin (CTX) is a snake toxin from the Taiwan cobra Naja naja. The cardiotoxin from the Malayan krait is called bucain. CTX perturb the membrane structure of cells by interaction with lipids. [1] For toxins in Proteopedia see Toxins. RelevanceCardiotoxin I causes necrosis of skeletal muscle cells. Cardiotoxin III induces apoptosis in K562 cells. 3D Structures of Cardiotoxin
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References
- ↑ Rees B, Samama JP, Thierry JC, Gilibert M, Fischer J, Schweitz H, Lazdunski M, Moras D. Crystal structure of a snake venom cardiotoxin. Proc Natl Acad Sci U S A. 1987 May;84(10):3132-6. PMID:3472200
