Image:PtGPX5 mechanism with Cys44+Cys92 disulfide EJJ 5-3-2022.tif
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PtGPX5_mechanism_with_Cys44+Cys92_disulfide_EJJ_5-3-2022.tif (file size: 1.05 MB, MIME type: image/tiff)
PtGPX5 mechanism. First, Cys44 of α1-helix scavenges the peroxide, and the helix locally twists and unfolds slightly to do this. This forms the Cys44-SOH sulfenic acid intermediate. Then, α2-helix completely unfolds into a flexible loop so that Cys92 can rapidly form a disulfide bond with the oxidized Cys44 residue.
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Date/Time | User | Dimensions | File size | Comment | |
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(current) | 12:22, 4 May 2022 | Emily Joyce (Talk | contribs) | 1.05 MB | PtGPX5 mechanism. First, Cys44 of α1-helix scavenges the peroxide, and the helix locally twists and unfolds slightly to do this. This forms the Cys44-SOH sulfenic acid intermediate. Then, α2-helix completely unfolds into a flexible loop so that Cys92 ca |
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