This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.

Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.

Rac GTPase-activating protein

From Proteopedia

Jump to: navigation, search

Human Rac GTPase-activating protein 1 GAP domain (grey) complex with CDC42 (green) and GDP (PDB code 5c2j)

Drag the structure with the mouse to rotate

3D structures of Rac GTPase-activating protein 1

Updated on 23-October-2017

3w6r, 2ovj – hRacGAP GAP domain – human
3wpq, 3wps – hRacGAP GAP domain (mutant)
4b6d – hRacGAP C1 domain
5c2j – hRacGAP GAP domain + CDC42 + GDP

References

↑ Wang SM, Ooi LL, Hui KM. Upregulation of Rac GTPase-activating protein 1 is significantly associated with the early recurrence of human hepatocellular carcinoma. Clin Cancer Res. 2011 Sep 15;17(18):6040-51. doi: 10.1158/1078-0432.CCR-11-0557. , Epub 2011 Aug 8. PMID:21825042 doi:http://dx.doi.org/10.1158/1078-0432.CCR-11-0557